Chuckmeister Posted October 2, 2004 Share Posted October 2, 2004 I'm wondering what metronidazole is and what symtoms it treats. Also what is the dosage rate? Thanks Charlie Link to comment Share on other sites More sharing options...
canerod Posted October 2, 2004 Share Posted October 2, 2004 hey Charlie metronidazole also goes under the trade names flagyl and Novonidazol in the US and Canada. It is used to treat infection and acne and as an antiprotozoal and was originally designed for human treatment. There is some evidence to suggest that it may have been shown to be carcinogenic in trials on rats and mice. Sorry cant help with info on fish treatment or dosage rates If you want a heap of tech mumbojumbo and other info goto http://aac.asm.org/cgi/content/full/43/7/1533 http://www.wedgewoodpharmacy.com/monograph...tronidazole.asp hth Bob Link to comment Share on other sites More sharing options...
Brett4Perth Posted October 2, 2004 Share Posted October 2, 2004 Hi Charlie, Metronizole (Flagyl) is a widely used antibiotic in human medicine. Its main application is for the treatment of anaerobes, particularly gut bacteria, but it is also effective against some protozoans eg. Giardia. Have never used it in fish personally. I would think it would be most effective orally (rather than in a bath solution). It is unlikely to be effective against Aeromonas/Pseudomonas or lots of other pathogens. As for being carcinogenic in rats and mice, these studies are usually done a very high dosages for prolonged periods. I wouldn't worry about this too much when treating fish for a week or so. Cheers Brett Link to comment Share on other sites More sharing options...
mtchye Posted October 2, 2004 Share Posted October 2, 2004 Hi guys, Brett, metronidazole is one of the few antibiotics shown to be effective as a bath rather than oral or injected. 6ppm is a widely documented dose rate, and number of treatments depends on target. Its active against gram negative anaerobes, as well as protozoans such as hexamita. Its fairly broad spectrum, but has a high therapeutic range so its hard to overdose on it. Its primary use is for elimination of protozoans such as hexamita, though it may have applications for bacterial infections due to its broad spectrum. It does not harm filter bacteria. Its available only via prescription by vet or doctor in australia. I believe its in the same family of drugs as 'Clout' and is thus also used to treat bloat on occasion. HTH Vincent Link to comment Share on other sites More sharing options...
Brett4Perth Posted October 3, 2004 Share Posted October 3, 2004 Hi Vince, Have you got a reference for that info about bath treatments, would be interested in reading it. Cheers Brett Link to comment Share on other sites More sharing options...
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